Epithelial to Mesenchymal Transition Promotes Breast Cancer Progression via a Fibronectin-dependent STAT3 Signaling Pathway

We previously established that overexpression of the EGF receptor (EGFR) is sufficient to induce tumor formation by otherwise nontransformed mammary epithelial cells, and that the initiation of epithelial-mesenchymal transition (EMT) is capable of increasing the invasion and metastasis of these cell...

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Главные авторы: Balanis, Nikolas, Wendt, Michael K., Schiemann, Barbara J., Wang, Zhenghe, Schiemann, William P., Carlin, Cathleen R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
Предметы:
Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689941/
https://ncbi.nlm.nih.gov/pubmed/23653350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.475277
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