Llwytho...

Pharmacokinetics of single ascending doses of the P-glycoprotein inhibitor tariquidar in healthy subjects

We assessed the pharmacokinetics (PK), tolerability and safety of tariquidar (TQD), a P-glycoprotein (Pgp) inhibitor, after i.v. administration of single ascending doses. Employed doses were up to 4-fold higher than in previous clinical trials in cancer patients and are capable to inhibit Pgp at the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bauer, M., Zeitlinger, M., Todorut, D., Böhmdorfer, M., Müller, M., Langer, O., Jäger, W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689924/
https://ncbi.nlm.nih.gov/pubmed/23146816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000343243
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