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Reactivation of the inactive X chromosome in development and reprogramming

In mammals, one of the two X chromosomes of female cells is inactivated for dosage compensation between the sexes. X chromosome inactivation is initiated in early embryos by the noncoding Xist RNA. Subsequent chromatin modifications on the inactive X chromosome (Xi) lead to a remarkable stability of...

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Detalhes bibliográficos
Main Authors: Ohhata, Tatsuya, Wutz, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: SP Birkhäuser Verlag Basel 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689915/
https://ncbi.nlm.nih.gov/pubmed/23052214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1174-3
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