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Effects of epidermal growth factor and 12-O-tetradecanoylphorbol-13-acetate on metabolism of the epidermal growth factor receptor in normal human fibroblasts.

The biosynthesis, phosphorylation, and degradation of the epidermal growth factor (EGF) receptor were examined in normal human fibroblasts. The receptor was initially synthesized as an Mr = 160,000 immature form which matured to an Mr = 170,000 form in a monensin-sensitive manner. Tunicamycin treatm...

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Bibliographic Details
Published in:Mol Cell Biol
Main Author: Decker, S J
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1984
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368978/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6208480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.4.9.1718-1724.1984
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