The Attenuated Brucella abortus Strain 19 Invades, Persists in, and Activates Human Dendritic Cells, and Induces the Secretion of IL-12p70 but Not IL-23

BACKGROUND: Bacterial vectors have been proposed as novel vaccine strategies to induce strong cellular immunity. Attenuated strains of Brucella abortus comprise promising vector candidates since they have the potential to induce strong CD4(+) and CD8(+) T-cell mediated immune responses in the absenc...

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Detalhes bibliográficos
Main Authors: Weinhold, Mario, Eisenblätter, Martin, Jasny, Edith, Fehlings, Michael, Finke, Antje, Gayum, Hermine, Rüschendorf, Ursula, Renner Viveros, Pablo, Moos, Verena, Allers, Kristina, Schneider, Thomas, Schaible, Ulrich E., Schumann, Ralf R., Mielke, Martin E., Ignatius, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689767/
https://ncbi.nlm.nih.gov/pubmed/23805193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065934
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