The Attenuated Brucella abortus Strain 19 Invades, Persists in, and Activates Human Dendritic Cells, and Induces the Secretion of IL-12p70 but Not IL-23

BACKGROUND: Bacterial vectors have been proposed as novel vaccine strategies to induce strong cellular immunity. Attenuated strains of Brucella abortus comprise promising vector candidates since they have the potential to induce strong CD4(+) and CD8(+) T-cell mediated immune responses in the absenc...

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Hlavní autoři: Weinhold, Mario, Eisenblätter, Martin, Jasny, Edith, Fehlings, Michael, Finke, Antje, Gayum, Hermine, Rüschendorf, Ursula, Renner Viveros, Pablo, Moos, Verena, Allers, Kristina, Schneider, Thomas, Schaible, Ulrich E., Schumann, Ralf R., Mielke, Martin E., Ignatius, Ralf
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689767/
https://ncbi.nlm.nih.gov/pubmed/23805193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065934
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