Myocardial Ablation of G Protein–Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway

Studies from our lab have shown that decreasing myocardial G protein–coupled receptor kinase 2 (GRK2) activity and expression can prevent heart failure progression after myocardial infarction. Since GRK2 appears to also act as a pro-death kinase in myocytes, we investigated the effect of cardiomyocy...

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Detalhes bibliográficos
Main Authors: Fan, Qian, Chen, Mai, Zuo, Lin, Shang, Xiying, Huang, Maggie Z., Ciccarelli, Michele, Raake, Philip, Brinks, Henriette, Chuprun, Kurt J., Dorn, Gerald W., Koch, Walter J., Gao, Erhe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689757/
https://ncbi.nlm.nih.gov/pubmed/23805205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066234
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