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New human transforming genes detected by a tumorigenicity assay.

We have developed a sensitive bioassay for transforming genes based on the tumorigenicity of cotransfected NIH3T3 cells in nude mice. The assay differs substantially from the NIH3T3 focus assay. Using it, we have detected the transfer of three transforming genes from the DNA of MCF-7, a human mammar...

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Main Authors: Fasano, O, Birnbaum, D, Edlund, L, Fogh, J, Wigler, M
Format: Artigo
Jezik:Inglês
Izdano: 1984
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC368975/
https://ncbi.nlm.nih.gov/pubmed/6092933
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