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DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation
Non-small cell lung cancer (NSCLC) patients treated with small molecule EGFR inhibitors, such as gefitinib, frequently develop drug resistance due to the presence of secondary mutations like the T790M mutation on EGFR exon 20. These mutations may originate from small subclonal populations in the pri...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689726/ https://ncbi.nlm.nih.gov/pubmed/23805327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067782 |
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