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Lability of the pAA Virulence Plasmid in Escherichia coli O104:H4: Implications for Virulence in Humans

BACKGROUND: Escherichia coli O104:H4 that caused the large German outbreak in 2011 is a highly virulent hybrid of enterohemorrhagic (EHEC) and enteroaggregative (EAEC) E. coli. The strain displays “stacked-brick” aggregative adherence to human intestinal epithelial cells mediated by aggregative adhe...

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Autors principals: Zhang, Wenlan, Bielaszewska, Martina, Kunsmann, Lisa, Mellmann, Alexander, Bauwens, Andreas, Köck, Robin, Kossow, Annelene, Anders, Agnes, Gatermann, Sören, Karch, Helge
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689698/
https://ncbi.nlm.nih.gov/pubmed/23805269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066717
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