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Antibiotic-Mediated Modulations of Outer Membrane Vesicles in Enterohemorrhagic Escherichia coli O104:H4 and O157:H7

Ciprofloxacin, meropenem, fosfomycin, and polymyxin B strongly increase production of outer membrane vesicles (OMVs) in Escherichia coli O104:H4 and O157:H7. Ciprofloxacin also upregulates OMV-associated Shiga toxin 2a, the major virulence factor of these pathogens, whereas the other antibiotics inc...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bauwens, Andreas, Kunsmann, Lisa, Karch, Helge, Mellmann, Alexander, Bielaszewska, Martina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571282/
https://ncbi.nlm.nih.gov/pubmed/28607018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00937-17
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