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Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures

DNA supercoiling is an inherent consequence of twisting DNA and is critical for regulating gene expression and DNA replication. However, DNA supercoiling at a genomic scale in human cells is uncharacterized. To map supercoiling we used biotinylated-trimethylpsoralen as a DNA structure probe to show...

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Bibliografski detalji
Glavni autori: Naughton, Catherine, Avlonitis, Nicolaos, Corless, Samuel, Prendergast, James G., Mati, Ioulia K., Eijk, Paul P., Cockroft, Scott L., Bradley, Mark, Ylstra, Bauke, Gilbert, Nick
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689368/
https://ncbi.nlm.nih.gov/pubmed/23416946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2509
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