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Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures
DNA supercoiling is an inherent consequence of twisting DNA and is critical for regulating gene expression and DNA replication. However, DNA supercoiling at a genomic scale in human cells is uncharacterized. To map supercoiling we used biotinylated-trimethylpsoralen as a DNA structure probe to show...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689368/ https://ncbi.nlm.nih.gov/pubmed/23416946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2509 |
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