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Pyrazolo[3,4-d]pyrimidines as inhibitor of anti-coagulation and inflammation activities of phospholipase A(2): insight from molecular docking studies

Phospholipase A(2) (PLA2), isolated from Daboia russelli pulchella (Russell’s viper), is enzymatically active as well as induces several pharmacological disorders including neurotoxicity, myotoxicity, cardiotoxicity, anti-coagulant, hemolytic, and platelet effects. Indomethacin reduces the effects o...

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Hlavní autoři: Yadava, Umesh, Singh, Maheshwer, Roychoudhury, Mihir
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689367/
https://ncbi.nlm.nih.gov/pubmed/23860918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-013-9299-7
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