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Sequences on the 3' side of hexanucleotide AAUAAA affect efficiency of cleavage at the polyadenylation site.

The hexanucleotide AAUAAA has been demonstrated to be part of the signal for cleavage and polyadenylation at appropriate sites on eucaryotic mRNA precursors. Since this sequence is not unique to polyadenylation sites, it cannot be the entire signal for the cleavage event. We have extended the defini...

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Autori principali: Sadofsky, M, Alwine, J C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1984
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC368935/
https://ncbi.nlm.nih.gov/pubmed/6149460
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