In Vivo Depletion of CD11c(+) Dendritic Cells Abrogates Priming of CD8(+) T Cells by Exogenous Cell-Associated Antigens

Cytotoxic T lymphocytes (CTL) respond to antigenic peptides presented on MHC class I molecules. On most cells, these peptides are exclusively of endogenous, cytosolic origin. Bone marrow-derived antigen-presenting cells, however, harbor a unique pathway for MHC I presentation of exogenous antigens....

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Main Authors: Jung, Steffen, Unutmaz, Derya, Wong, Phillip, Sano, Gen-Ichiro, De los Santos, Kenia, Sparwasser, Tim, Wu, Shengji, Vuthoori, Sri, Ko, Kyung, Zavala, Fidel, Pamer, Eric G., Littman, Dan R., Lang, Richard A.
Format: Artigo
Language:Inglês
Published: 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689299/
https://ncbi.nlm.nih.gov/pubmed/12196292
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