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Characterization of a novel NKG2D and NKp46 double-mutant mouse reveals subtle variations in the NK cell repertoire

The immunoreceptors NKG2D and NKp46 are known for their capacity to activate natural killer (NK) cell cytotoxicity and secretory responses in the contexts of tumors and infections, yet their roles in NK cell education remain unclear. Here, we provide the first characterization of mice deficient for...

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Bibliografiske detaljer
Main Authors: Sheppard, Sam, Triulzi, Chiara, Ardolino, Michele, Serna, Daniel, Zhang, Lily, Raulet, David H., Guerra, Nadia
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689249/
https://ncbi.nlm.nih.gov/pubmed/23649470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-471607
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