Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions

BACKGROUND: Persistent high risk HPV infection can lead to cervical cancer, the second most common malignant tumor in women worldwide. NK cells play a crucial role against tumors and virus-infected cells through a fine balance between activating and inhibitory receptors. Expression of triggering rec...

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Detalhes bibliográficos
Main Authors: Garcia-Iglesias, Trinidad, del Toro-Arreola, Alicia, Albarran-Somoza, Benibelks, del Toro-Arreola, Susana, Sanchez-Hernandez, Pedro E, Ramirez-Dueñas, Maria Guadalupe, Balderas-Peña, Luz Ma. Adriana, Bravo-Cuellar, Alejandro, Ortiz-Lazareno, Pablo C, Daneri-Navarro, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704222/
https://ncbi.nlm.nih.gov/pubmed/19531227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-186
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