The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis

We have investigated the importance of interleukin-6 (IL-6) in promoting tumor growth and metastasis. In human primary breast cancers, increased levels of IL-6 were found at the tumor leading edge and positively correlated with advanced stage, suggesting a mechanistic link between tumor cell product...

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Detaylı Bibliyografya
Asıl Yazarlar: Chang, Qing, Bournazou, Eirini, Sansone, Pasquale, Berishaj, Marjan, Gao, Sizhi Paul, Daly, Laura, Wels, Jared, Theilen, Till, Granitto, Selena, Zhang, Xinmin, Cotari, Jesse, Alpaugh, Mary L, de Stanchina, Elisa, Manova, Katia, Li, Ming, Bonafe, Massimiliano, Ceccarelli, Claudio, Taffurelli, Mario, Santini, Donatella, Altan-Bonnet, Gregoire, Kaplan, Rosandra, Norton, Larry, Nishimoto, Norihiro, Huszar, Dennis, Lyden, David, Bromberg, Jacqueline
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Neoplasia Press Inc. 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689247/
https://ncbi.nlm.nih.gov/pubmed/23814496
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