Multimodal Microvascular Imaging Reveals that Selective Inhibition of Class I PI3K Is Sufficient to Induce an Antivascular Response

The phosphatidylinositol 3-kinase (PI3K) pathway is a central mediator of vascular endothelial growth factor (VEGF)-driven angiogenesis. The discovery of small molecule inhibitors that selectively target PI3K or PI3K and mammalian target of rapamycin (mTOR) provides an opportunity to pharmacological...

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Detalhes bibliográficos
Main Authors: Sampath, Deepak, Oeh, Jason, Wyatt, Shelby K, Cao, Tim C, Koeppen, Hartmut, Eastham-Anderson, Jeffrey, Robillard, Liliane, Ho, Calvin C K, Ross, Jed, Zhuang, Guanglei, Reslan, Hani Bou, Vitorino, Philip, Barck, Kai H, Ungersma, Sharon E, Vernes, Jean Michel, Caunt, Maresa, Van Bruggen, Nick, Ye, Weilan, Vijapurkar, Ulka, Meng, Yu-Ju Gloria, Ferrara, Napoleone, Friedman, Lori S, Carano, Richard A D
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689233/
https://ncbi.nlm.nih.gov/pubmed/23814482
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