Use of Quantitative Broad-based Polymerase Chain Reaction for Detection and Identification of Common Bacterial Pathogens in Cerebrospinal Fluid

BACKGROUND: Conventional laboratory diagnosis of bacterial meningitis based on microscopy followed by culture is time-consuming and has only moderate sensitivity. OBJECTIVES: The objective was to define the limit of detection (LOD), analytic specificity, and performance characteristics of a broad-ba...

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Hlavní autoři: Rothman, Richard, Ramachandran, Padmini, Yang, Samuel, Hardick, Andrew, Won, Helen, Kecojevic, Aleksandar, Quianzon, Celeste, Hsieh, Yu-Hsiang, Gaydos, Charlotte
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689214/
https://ncbi.nlm.nih.gov/pubmed/20653589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1553-2712.2010.00790.x
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