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An Amino Acid Residue in the Second Extracellular Loop Determines the Agonist-Dependent Tolerance Property of the Human D3 Dopamine Receptor

[Image: see text] The D3 dopamine receptor is a therapeutic target for treating various nervous system disorders such as schizophrenia, Parkinson’s disease, depression, and addictive behaviors. The crystal structure of the D3 receptor bound to an antagonist was recently described; however, the struc...

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Bibliografische gegevens
Hoofdauteurs: Gil-Mast, Sara, Kortagere, Sandhya, Kota, Kokila, Kuzhikandathil, Eldo V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2013
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689203/
https://ncbi.nlm.nih.gov/pubmed/23477444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn3002202
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