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An Amino Acid Residue in the Second Extracellular Loop Determines the Agonist-Dependent Tolerance Property of the Human D3 Dopamine Receptor

[Image: see text] The D3 dopamine receptor is a therapeutic target for treating various nervous system disorders such as schizophrenia, Parkinson’s disease, depression, and addictive behaviors. The crystal structure of the D3 receptor bound to an antagonist was recently described; however, the struc...

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Detalhes bibliográficos
Main Authors: Gil-Mast, Sara, Kortagere, Sandhya, Kota, Kokila, Kuzhikandathil, Eldo V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689203/
https://ncbi.nlm.nih.gov/pubmed/23477444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn3002202
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