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An integrated multidisciplinary model describing initiation of cancer and the Warburg hypothesis
BACKGROUND: In this paper we propose a chemical physics mechanism for the initiation of the glycolytic switch commonly known as the Warburg hypothesis, whereby glycolytic activity terminating in lactate continues even in well-oxygenated cells. We show that this may result in cancer via mitotic failu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689044/ https://ncbi.nlm.nih.gov/pubmed/23758735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-10-39 |
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