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A Transient Upregulation of Glutamine Synthetase in the Dentate Gyrus Is Involved in Epileptogenesis Induced by Amygdala Kindling in the Rat

Reduction of glutamine synthetase (GS) function is closely related to established epilepsy, but little is known regarding its role in epileptogenesis. The present study aimed to elucidate the functional changes of GS in the brain and its involvement in epileptogenesis using the amygdala kindling mod...

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Detalhes bibliográficos
Main Authors: Sun, Hong-Liu, Zhang, Shi-Hong, Zhong, Kai, Xu, Zheng-Hao, Feng, Bo, Yu, Jie, Fang, Qi, Wang, Shuang, Wu, Deng-Chang, Zhang, Jian-Min, Chen, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688959/
https://ncbi.nlm.nih.gov/pubmed/23825580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066885
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