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Gene Expression Profiling of Gliadin Effects on Intestinal Epithelial Cells Suggests Novel Non-Enzymatic Functions of Pepsin and Trypsin

Gliadin triggers T-cell mediated immunity in celiac disease, and has cytotoxic effects on enterocytes mediated through obscure mechanisms. In addition, gliadin transport mechanisms, potential cell surface receptors and gliadin-activated downstream signaling pathways are not completely understood. In...

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Detalhes bibliográficos
Main Authors: Parmar, Amarjit, Greco, Dario, Venäläinen, Jarkko, Gentile, Massimiliano, Dukes, Emma, Saavalainen, Päivi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688875/
https://ncbi.nlm.nih.gov/pubmed/23824913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066307
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