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Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe

BACKGROUND: Controlled human malaria infection (CHMI) studies have become a routine tool to evaluate efficacy of candidate anti-malarial drugs and vaccines. To date, CHMI trials have mostly been conducted using the bite of infected mosquitoes, restricting the number of trial sites that can perform C...

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Main Authors: Sheehy, Susanne H., Spencer, Alexandra J., Douglas, Alexander D., Sim, B. Kim Lee, Longley, Rhea J., Edwards, Nick J., Poulton, Ian D., Kimani, Domtila, Williams, Andrew R., Anagnostou, Nicholas A., Roberts, Rachel, Kerridge, Simon, Voysey, Merryn, James, Eric R., Billingsley, Peter F., Gunasekera, Anusha, Lawrie, Alison M., Hoffman, Stephen L., Hill, Adrian V. S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688861/
https://ncbi.nlm.nih.gov/pubmed/23823332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065960
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