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Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells

Indolic and kynuric pathways of skin melatonin metabolism were monitored by liquid chromatography mass spectrometry in human keratinocytes, melanocytes, dermal fibroblasts, and melanoma cells. Production of 6-hydroxymelatonin [6(OH)M], N(1)-acetyl-N(2)-formyl-5-methoxykynuramine (AFMK) and 5-methoxy...

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Detalhes bibliográficos
Main Authors: Kim, Tae-Kang, Kleszczyński, Konrad, Janjetovic, Zorica, Sweatman, Trevor, Lin, Zongtao, Li, Wei, Reiter, Russel J., Fischer, Tobias W., Slominski, Andrzej T.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688757/
https://ncbi.nlm.nih.gov/pubmed/23620527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-224691
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