Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells

Indolic and kynuric pathways of skin melatonin metabolism were monitored by liquid chromatography mass spectrometry in human keratinocytes, melanocytes, dermal fibroblasts, and melanoma cells. Production of 6-hydroxymelatonin [6(OH)M], N(1)-acetyl-N(2)-formyl-5-methoxykynuramine (AFMK) and 5-methoxy...

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Hlavní autoři: Kim, Tae-Kang, Kleszczyński, Konrad, Janjetovic, Zorica, Sweatman, Trevor, Lin, Zongtao, Li, Wei, Reiter, Russel J., Fischer, Tobias W., Slominski, Andrzej T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2013
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688757/
https://ncbi.nlm.nih.gov/pubmed/23620527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-224691
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