Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells

Indolic and kynuric pathways of skin melatonin metabolism were monitored by liquid chromatography mass spectrometry in human keratinocytes, melanocytes, dermal fibroblasts, and melanoma cells. Production of 6-hydroxymelatonin [6(OH)M], N(1)-acetyl-N(2)-formyl-5-methoxykynuramine (AFMK) and 5-methoxy...

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Bibliografski detalji
Glavni autori: Kim, Tae-Kang, Kleszczyński, Konrad, Janjetovic, Zorica, Sweatman, Trevor, Lin, Zongtao, Li, Wei, Reiter, Russel J., Fischer, Tobias W., Slominski, Andrzej T.
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2013
Teme:
Research Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688757/
https://ncbi.nlm.nih.gov/pubmed/23620527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-224691
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