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Systemic Autoimmunity in TAM Triple Knockout Mice Causes Inflammatory Brain Damage and Cell Death

The Tyro3, Axl and Mertk (TAM) triply knockout (TKO) mice exhibit systemic autoimmune diseases, with characteristics of increased proinflammatory cytokine production, autoantibody deposition and autoreactive lymphocyte infiltration into a variety of tissues. Here we show that TKO mice produce high l...

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Hlavní autoři: Li, Qiutang, Lu, Qingjun, Lu, Huayi, Tian, Shifu, Lu, Qingxian
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688737/
https://ncbi.nlm.nih.gov/pubmed/23840307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064812
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