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Systemic Autoimmunity in TAM Triple Knockout Mice Causes Inflammatory Brain Damage and Cell Death

The Tyro3, Axl and Mertk (TAM) triply knockout (TKO) mice exhibit systemic autoimmune diseases, with characteristics of increased proinflammatory cytokine production, autoantibody deposition and autoreactive lymphocyte infiltration into a variety of tissues. Here we show that TKO mice produce high l...

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Detalhes bibliográficos
Main Authors: Li, Qiutang, Lu, Qingjun, Lu, Huayi, Tian, Shifu, Lu, Qingxian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688737/
https://ncbi.nlm.nih.gov/pubmed/23840307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064812
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