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Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism for Catalysis

ADP-dependent glucokinases represent a unique family of kinases that belong to the ribokinase superfamily, being present mainly in hyperthermophilic archaea. For these enzymes there is no agreement about the magnitude of the structural transitions associated with ligand binding and whether they are...

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Detalhes bibliográficos
Main Authors: Rivas-Pardo, Jaime Andrés, Herrera-Morande, Alejandra, Castro-Fernandez, Victor, Fernandez, Francisco J., Vega, M. Cristina, Guixé, Victoria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688580/
https://ncbi.nlm.nih.gov/pubmed/23818958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066687
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