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The Rho GTPase inactivation domain in Vibrio cholerae MARTX toxin has a circularly permuted papain-like thiol protease fold

A Rho GTPase inactivation domain (RID) has been discovered in the multifunctional, autoprocessing RTX toxin RtxA from Vibrio cholerae. The RID domain causes actin depolymerization and rounding of host cells through inactivation of the small Rho GTPases Rho, Rac and Cdc42. With only a few toxin prote...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pei, Jimin, Grishin, Nick V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688474/
https://ncbi.nlm.nih.gov/pubmed/19434753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22447
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