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Immunoglobulin class switching appears to be regulated by B cell antigen receptor-specific T cell action
Antigen affinity is commonly viewed as the driving force behind the selection for dominant clonotypes that can occur during the T cell-dependent processes of class switch recombination (CSR) and immune maturation. To test this view, we analyzed the variable gene repertoires of natural monoclonal ant...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3688080/ https://ncbi.nlm.nih.gov/pubmed/22531925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141857 |
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