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Solubility Enhancement of a Poorly Water Soluble Drug by Forming Solid Dispersions using Mechanochemical Activation

Mechanochemical activation is a practical cogrinding operation used to obtain a solid dispersion of a poorly water soluble drug through changes in the solid state molecular aggregation of drug-carrier mixtures and the formation of noncovalent interactions (hydrogen bonds) between two crystalline sol...

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Main Authors: Rojas-Oviedo, I., Retchkiman-Corona, B., Quirino-Barreda, C. T., Cárdenas, J., Schabes-Retchkiman, P. S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Medknow Publications & Media Pvt Ltd 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687919/
https://ncbi.nlm.nih.gov/pubmed/23798775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0250-474X.110576
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