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Solid Dispersion as an Approach for Bioavailability Enhancement of Poorly Water-Soluble Drug Ritonavir

Ritonavir is an antiretroviral drug characterized by low solubility and high permeability which corresponds to BCS class II drug. The purpose of the study was to develop solid dispersion by different methods and investigate them for in vitro and in vivo performance for enhancing dissolution and bioa...

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Détails bibliographiques
Auteurs principaux: Sinha, Shilpi, Ali, Mushir, Baboota, Sanjula, Ahuja, Alka, Kumar, Anil, Ali, Javed
Format: Artigo
Langue:Inglês
Publié: Springer US 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902348/
https://ncbi.nlm.nih.gov/pubmed/20238187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9404-1
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