Effects of 5-azacytidine on methylation and expression of specific DNA sequences in C3H 10T1/2 cells.

The present study indicates that the transient exposure of C3H 10T1/2 mouse embryo fibroblasts to 5-azacytidine leads to extensive loss of methylation of the protooncogene c-mos and the beta-globin locus at the cell population level and in at least 40 isolated subclones. These changes persisted, eve...

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Udgivet i:Mol Cell Biol
Main Authors: Hsiao, W L, Gattoni-Celli, S, Kirschmeier, P, Weinstein, I B
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368771/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6201721/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.4.4.634
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