Effects of 5-azacytidine on methylation and expression of specific DNA sequences in C3H 10T1/2 cells.
The present study indicates that the transient exposure of C3H 10T1/2 mouse embryo fibroblasts to 5-azacytidine leads to extensive loss of methylation of the protooncogene c-mos and the beta-globin locus at the cell population level and in at least 40 isolated subclones. These changes persisted, eve...
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| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1984
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6201721/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.4.4.634-641.1984 |
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