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Polymeric immunoglobulin receptor traffics through two distinct apically targeted pathways in primary lacrimal gland acinar cells

The polymeric immunoglobulin receptor (pIgR) mediates transcytosis of dimeric immunoglobulin A (dIgA) and its release into mucosal secretions. The present study reveals the complexity of the trafficking of pIgR to the apical plasma membrane in epithelial cells with exocrine secretory functions; in r...

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Detalhes bibliográficos
Main Authors: Xu, Shi, Ma, Linlin, Evans, Eunbyul, Okamoto, Curtis T., Hamm-Alvarez, Sarah F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687702/
https://ncbi.nlm.nih.gov/pubmed/23606742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.122242
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