Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging

While environmental stress likely plays a significant role in promoting aging, the relationship remains poorly understood. In order to characterize this interaction in a more comprehensive manner, we examined the stress response profiles for 46 long-lived yeast mutant strains across four different s...

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Hauptverfasser: Delaney, Joe R., Ahmed, Umema, Chou, Annie, Sim, Sylvia, Carr, Daniel, Murakami, Christopher J., Schleit, Jennifer, Sutphin, George L., An, Elroy H., Castanza, Anthony, Fletcher, Marissa, Higgins, Sean, Jelic, Monika, Klum, Shannon, Muller, Brian, Peng, Zhao J., Rai, Dilreet, Ros, Vanessa, Singh, Minnie, Wende, Helen Vander, Kennedy, Brian K., Kaeberlein, Matt
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687586/
https://ncbi.nlm.nih.gov/pubmed/23167605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12032
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