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Human Rad51 Promotes Mitochondrial DNA Synthesis Under Conditions of Increased Replication Stress

Homologous recombination is essential for productive DNA replication particularly under stress conditions. We previously demonstrated a stress-induced recruitment of Rad51 to mitochondria and a critical need for its activity in the maintenance of mitochondrial DNA (mtDNA) copy number. Using the huma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sage, Jay M., Knight, Kendall L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687551/
https://ncbi.nlm.nih.gov/pubmed/23591384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2013.04.004
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