Accurate Structure Prediction of Peptide-MHC Complexes for Identifying Highly Immunogenic Antigens

Designing an optimal HIV-1 vaccine faces the challenge of identifying antigens that induce a broad immune capacity. One factor to control the breadth of T cell responses is the surface morphology of a peptide-MHC complex. Here, we present an in silico protocol for predicting peptide-MHC structure. A...

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Hlavní autoři: Park, Min-Sun, Park, Sung Yong, Miller, Keith R., Collins, Edward J., Lee, Ha Youn
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686981/
https://ncbi.nlm.nih.gov/pubmed/23688437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2013.04.011
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