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T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen

While recent evidence strongly suggests that the third complementarity determining regions (CDR3s) of T cell receptors (TCRs) directly contact antigenic peptides bound to major histocompatibility complex (MHC) molecules, the nature of other TCR contact(s) is less clear. Here we probe the extent to w...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191102/
https://ncbi.nlm.nih.gov/pubmed/8393480
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