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Rescue of functional replication origins from embedded configurations in a plasmid carrying the adenovirus genome.

A variant of the adenovirus type 5 genome which lacks EcoRI sites has been cloned in a bacterial plasmid after the addition of EcoRI oligonucleotide linkers to its ends. Closed circular forms of the recombinant viral genome were not infectious upon their introduction into permissive eucaryotic cells...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: Hanahan, D, Gluzman, Y
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1984
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368696/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6700592/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.4.2.302
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