RNA-Seq Differentiates Tumour and Host mRNA Expression Changes Induced by Treatment of Human Tumour Xenografts with the VEGFR Tyrosine Kinase Inhibitor Cediranib

Pre-clinical models of tumour biology often rely on propagating human tumour cells in a mouse. In order to gain insight into the alignment of these models to human disease segments or investigate the effects of different therapeutics, approaches such as PCR or array based expression profiling are of...

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Detalhes bibliográficos
Main Authors: Bradford, James R., Farren, Matthew, Powell, Steve J., Runswick, Sarah, Weston, Susie L., Brown, Helen, Delpuech, Oona, Wappett, Mark, Smith, Neil R., Carr, T. Hedley, Dry, Jonathan R., Gibson, Neil J., Barry, Simon T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686868/
https://ncbi.nlm.nih.gov/pubmed/23840389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066003
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