Chromosome-mediated gene transfer of hydroxyurea resistance and amplification of ribonucleotide reductase activity.

Metaphase chromosomes purified from a hydroxyurea-resistant Chinese hamster cell line were able to transform recipient wild-type cells to hydroxyurea resistance at a frequency of 10(-6). Approximately 60% of the resulting transformant clones gradually lost hydroxyurea resistance when cultivated for...

Full description

Saved in:
Bibliographic Details
Main Authors: Lewis, W H, Srinivasan, P R
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC368634/
https://ncbi.nlm.nih.gov/pubmed/6308422
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items