Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects

OBJECTIVE: Lumbar disc degeneration (LDD) is an important cause of low back pain, which is a common and costly problem. LDD is characterised by disc space narrowing and osteophyte growth at the circumference of the disc. To date, the agnostic search of the genome by genome-wide association (GWA) to...

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Detalhes bibliográficos
Main Authors: Williams, Frances M K, Bansal, Aruna T, van Meurs, Joyce B, Bell, Jordana T, Meulenbelt, Ingrid, Suri, Pradeep, Rivadeneira, Fernando, Sambrook, Philip N, Hofman, Albert, Bierma-Zeinstra, Sita, Menni, Cristina, Kloppenburg, Margreet, Slagboom, P Eline, Hunter, David J, MacGregor, Alex J, Uitterlinden, Andre G, Spector, Tim D
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2013
Assuntos:
Clinical and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686263/
https://ncbi.nlm.nih.gov/pubmed/22993228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2012-201551
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