GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women

OBJECTIVE: Lumbar disc degeneration (LDD) is a serious social and medical problem which has been shown to be highly heritable. It has similarities with peripheral joint osteoarthritis (OA) in terms of both epidemiology and pathologic processes. A few known genetic variants have been identified using...

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Detalhes bibliográficos
Main Authors: Williams, F M K, Popham, M, Hart, D J, de Schepper, E, Bierma-Zeinstra, S, Hofman, A, Uitterlinden, A G, Arden, N K, Cooper, C, Spector, T D, Valdes, A M, van Meurs, J
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
Assuntos:
Cartilage/Disc Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498734/
https://ncbi.nlm.nih.gov/pubmed/21360499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30169
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