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Nickel inhibits β-1 adrenoceptor mediated activation of cardiac CFTR chloride channels
Cardiac ventricular myocytes exhibit a protein kinase A-dependent Cl(−) current (I(Cl.PKA)) mediated by the cystic fibrosis transmembrane conductance regulator (CFTR). There is conflicting evidence regarding the ability of the divalent cation nickel (Ni(2+)), which has been used widely in vitro in t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Academic Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3686155/ https://ncbi.nlm.nih.gov/pubmed/23376720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.01.087 |
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