Modulation of 5-Lipoxygenase in Proteotoxicity and Alzheimer's Disease

The accumulation of intracellular β amyloid (Aβ) may be one of the factors leading to neuronal cell death in Alzheimer's disease (AD). Using a pyrazole called CNB-001, which was selected for its ability to reduce intracellular Aβ, we show that the activation of the eIF2α/ATF4 arm of the unfolde...

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Detaylı Bibliyografya
Asıl Yazarlar: Valera, Elvira, Dargusch, Richard, Maher, Pamela A., Schubert, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2013
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685841/
https://ncbi.nlm.nih.gov/pubmed/23785163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5183-12.2013
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