In vitro methylation of specific regions of the cloned Moloney sarcoma virus genome inhibits its transforming activity.

The transforming activity of cloned Moloney sarcoma virus (MSV) proviral DNA was inhibited by in vitro methylation of the DNA at cytosine residues, using HpaII and HhaI methylases before transfection into NIH 3T3 cells. The inhibition of transforming activity due to HpaII methylation was reversed by...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	McGeady, M L, Jhappan, C, Ascione, R, Vande Woude, G F
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1983
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368539/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6843547/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.3.305-314.1983
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